Biochemical effects of some organophosphorus pesticides on the ovaries of albino rats.
نویسندگان
چکیده
An evaluation of the toxic effects of three organophosphates; monocrotophos, dimethoate and methyl parathion on female reproduction was made by biochemical estimations of cytoplasmic and membrance bound proteins, lipids, phospholipids and cholesterol in the rat ovaries after treatment with their low residual level doses (LD50 1/8-1/5) to three groups of six rats each for 90 days. All the three pesticides caused degenerative changes in the ovaries as evidenced by a significant decrease in the concentration of cytoplasmic as well as membrane bound proteins, total lipids, phospholipids and cholesterol. The observations are thus indicative of the reproductive toxicity caused by organophosphates at cellular and molecular level in the ovaries of rats.
منابع مشابه
Enzymatic changes induced by some organophosphorus pesticides in female rats.
An evaluation of toxic effects of three organophosphorus pesticides viz. monocrotophos, methyl parathion and dimethoate given orally daily for 90 days was done in terms of enzymatic changes in plasma and liver of female albino rats. A significant decrease was observed in the level of esterases in plasma with all the three pesticides. The activity of acid and alkaline phosphatases and aminotrans...
متن کاملEvaluation of the effects of chronic exposure to organophosphorus pesticides on thyroid function
متن کامل
Protective effects of vitamin D on ischemia-reperfusion injury of the ovary in a rat model
Objective(s): The aim of the present study is to investigate probable acute effects of vitamin D on ischemia-reperfusion injury in the rat ovary.Materials and Methods: A group of 30 Wistar albino rats was divided into five groups of 6 each. Group 1: underwent laparotomy only and the ovaries were removed. Group 2: 3-hr ischemia followed by excision of the ovaries. Group 3: 3-hr ischemia and 3...
متن کاملToxicological Assessment of Solanum Erianthum Extracts in Albino Rats: Haematological, biochemical and histopathological findings
Background: Solanum erianthum leaves extract has been used to treat sexually-transmitted diseases, malaria, and leprosy. This study assessed the toxicity and safety of S. erianthum extract in rats. Methods: Treatment with 250, 500 or 750 mg/kg of the aqueous, ethanolic and methanolic extracts in the rats had different effects on the biochemical activities of the liver, heart and kidneys, and ...
متن کاملEffect of celery,sour apple and carrot in some of serum biochemical parameters of diabetic rats
In order to investigate the effect of celery,sour apple and carrot on some of the biochemical parameters of serum from diabetic rats,25 male adult rats were selected.the rats were divided into 5 groups.a group consisting of 5 rats were chosen as the control group and diabetes mellitus was induced in 20 out of 25 adult male albino rats using intraperitoneal injection of 170mg/kg(body weight) of ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Indian journal of physiology and pharmacology
دوره 49 2 شماره
صفحات -
تاریخ انتشار 2005